How Does Acetylcholine Stimulate Muscle Contraction? Skeletal muscle contraction and changes with exercise. (A) Neurotransmitter (acetylcholine, ACh) released from nerve endings binds to receptors (AChRs) on the muscle surface. The ensuing depolarization causes sodium channels to open, which elicits an action potential that propagates along the cell. How does acetylcholine affect muscle contraction? When acetylcholine
What Happens When Acetylcholine Is Blocked? The acetylcholine receptor is an essential link between the brain and the muscles, so it is a sensitive location for attack. Many organisms make poisons that block the acetylcholine receptor, causing paralysis. What would happen to someone if an antagonist blocked transmission of acetylcholine? By blocking the actions of
What Happens If You Have Too Much Acetylcholine? Excessive accumulation of acetylcholine (ACh) at the neuromuscular junctions and synapses causes symptoms of both muscarinic and nicotinic toxicity. These include cramps, increased salivation, lacrimation, muscular weakness, paralysis, muscular fasciculation, diarrhea, and blurry vision. Is too much acetylcholine bad? Supplements that raise acetylcholine levels are safe for