chemical mutagens

What Is The Implication If There Is A Positive Result In An Ames Test?

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What Is The Implication If There Is A Positive Result In An Ames Test? a) An Ames positive test usually results in a carcinogenic effect observed in the 2-year rodent bioassay. Using a database of 709 carcinogens, Cheeseman et al. What does the Ames test determine? The Ames test is used world-wide as an initial

How Do Intercalating Agents Cause Mutations?

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How Do Intercalating Agents Cause Mutations? Insertion of these agents distorts the DNA double helix, thereby interfering with DNA replication, transcription, and repair. Such DNA distortions often result in mutations, so intercalating agents are also mutagens. How do biological agents cause mutations? Biological agents of mutation are sources of DNA from elements like transposons and