Why Should You Not Crush Ibuprofen?

Why Should You Not Crush Ibuprofen? Crushing these tablets therefore may not seriously affect how the drug is released but may cause the resultant mixture to be unpleasant to taste which is likely to negatively affect adherence. Examples: Quinine sulphate. Ibuprofen. Can ibuprofen be dissolved in water? Ibuprofen is badly water soluble drug and distilled