How Does Cholera Toxin Affect G Protein Signalling?
How Does Cholera Toxin Affect G Protein Signalling? Cholera toxin, by acting as a classical A-B type toxin, leads to ADP-ribosylation of G protein, and constitutive activation of AC, thereby giving rise to increased levels of cyclic AMP within the host cell (Fig. 1). How does cholera toxin affect G protein signaling? The catalytic portion