What Are The Side Effects Of A Colon Cleanse?

What Are The Side Effects Of A Colon Cleanse? Colon cleansing can also cause less serious side effects, such as cramping, bloating, diarrhea, nausea and vomiting. Other potential concerns with colon cleansing include: Dehydration. A tear in the rectum (perforation) What are some of the possible side effects of colon cleanses? Dehydration. Vomiting, nausea, cramps.