How Does Cyanide Inhibit Complex 4?
How Does Cyanide Inhibit Complex 4? Cyanide binds to Fe3 + in heme-containing proteins. This inhibits the terminal cytochrome complex IV of the electron transport chain. The blocklock of complex IV by cyanide depletes ATP culminating in cell death. … In severe cyanide poisoning, autonomic shock due to the release of biogenic amines plays a