What Interferes With The Depo Shot?

What Interferes With The Depo Shot? Examples include griseofulvin, modafinil, rifamycins (such as rifampin, rifabutin), St. John’s wort, drugs used to treat seizures (such as barbiturates, carbamazepine, felbamate, phenytoin, primidone, topiramate), HIV drugs (such as nelfinavir, nevirapine, ritonavir), among others. Does grapefruit affect the depo? While grapefruit normally will not lower the effectiveness of the