Is Depo-Provera Affected By Antibiotics?

Is Depo-Provera Affected By Antibiotics? Neither antibiotics nor antiseizure medicines reduce Depo-Provera’s effectiveness. The only drug which reduces its effectiveness is aminoglutethimide (Cytadren), used to suppress adrenal function in some people with Cushing syndrome. Research indicates that Depo-Provera even reduces the frequency of seizures. What medications affect Depo-Provera? barbiturates. bosentan. carbamazepine. felbamate. griseofulvin. oxcarbazepine. phenytoin.