How Does Drugs Work In The Body? Drugs interfere with the way neurons send, receive, and process signals via neurotransmitters. Some drugs, such as marijuana and heroin, can activate neurons because their chemical structure mimics that of a natural neurotransmitter in the body. This allows the drugs to attach onto and activate the neurons. How
Does Volume Of Distribution Change With Age? The volume of distribution is decreased in elderly patients. As a result, loading doses should be reduced by approximately 20%[60]. How does age affect drug distribution? In general drug absorption, distribution in the body, activity, metabolism and excretion can all change as a result of ageing. The older
What Are Three Factors That Can Interfere With The Therapeutic Effects Of A Drug? Therapy-related factors identified include: route of administration, treatment complexity, duration of treatment period, medication side effects, degree of behavioral change required, taste of medication and requirement for drug storage (Table 4). What are 3 risk factors that can cause a decrease