enzyme cofactors

What Are Common Enzyme Cofactors? As many as 120 enzymes require one of these coenzymes as cofactors; these include decarboxylases, dehydratases, desulfydrases, racemases, synthases, and transaminases. Pyridoxal phosphate and pyridoxamine phosphate are also involved in the break-down of amino acids, the building blocks of proteins. What are the three types of cofactors? Prosthetic groups. Coenzymes.