What Receptors Does Norepinephrine Stimulate?

What Receptors Does Norepinephrine Stimulate? Norepinephrine can then go on to bind three main receptors: alpha1 (alpha-1), alpha-2, and beta receptors. These receptors classify as G-protein coupled receptors with either inhibitory or excitatory effects and different binding affinities to norepinephrine. What receptors increases norepinephrine release? NE stimulates prejunctional alpha2-adrenergic receptors to inhibit the further release