esterification reaction

Can Fisher Esterification Use A Base?

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Can Fisher Esterification Use A Base? Fischer-Speier Esterification. The Lewis or Brønstedt acid-catalyzed esterification of carboxylic acids with alcohols to give esters is a typical reaction in which the products and reactants are in equilibrium. Why is Naoh not used in Fischer esterification? Sodium hydroxide is a much stronger base and better nucleophile than sodium

What Is A Disadvantage Of Fischer Esterification?

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What Is A Disadvantage Of Fischer Esterification? The primary disadvantages of Fischer esterification routes are its thermodynamic reversibility and relatively slow reaction rates—often on the scale of several hours to years, depending on the reaction conditions. Why is Fischer esterification slow? In general, it is a slow reaction carried out in reflux using a strong