How Does Estrogen Metabolism Play A Role In Breast Cancer Risk?
How Does Estrogen Metabolism Play A Role In Breast Cancer Risk? 4-hydroxylated catechol estrogens possess carcinogenic potential due to their ability to cause DNA damage by forming depurinating adducts, which in turn, generate mutations with subsequent oxidative damage and initiation of breast cancer [37]. How does estrogen affect breast cancer? Because the female hormone estrogen