Are Exotoxins Destroyed By Heat? Most exotoxins can be destroyed by heating. They may exert their effect locally or produce systemic effects. (Nester, 2007). Well known exotoxins include the botulinum toxin produced by Clostridium botulinum, the Corynebacterium diphtheriae exotoxin which is produced during life threatening symptoms of diphtheria. Are exotoxins immunogenic? Exotoxins are highly immunogenic.
Can Be Converted Into Toxoid? Toxoid vaccines (e.g. vaccines for diphtheria and tetanus) are made by purifying the bacterial exotoxin (Flow Chart 26.3). Toxicity of purified exotoxins is then suppressed or inactivated either by heat or with formaldehyde (while maintaining immunogenicity) to form toxoids. Which toxins can be converted into toxoid by formaldehyde? Diphtheria toxoid
When Do Bacteria Release Toxins? Bacteria generate toxins which can be classified as either exotoxins or endotoxins. Exotoxins are generated and actively secreted; endotoxins remain part of the bacteria. Usually, an endotoxin is part of the bacterial outer membrane, and it is not released until the bacterium is killed by the immune system. Why do
Do Exotoxins Cause Fever? Do Exotoxins cause fever? The pyrogenic exotoxins A, B, C, MF, and SSA, also called scarlatina toxins and erythrogenic toxins, induce lymphocyte blastogenesis, potentiate endotoxin-induced shock,36 induce fever, suppress antibody synthesis, and act as superantigens. Do exotoxins produce fever? S.N. Exotoxins Endotoxins 8 Usually binds to specific receptors Specific receptors not