Why Does Nondisjunction Increase With Maternal Age?
Why Does Nondisjunction Increase With Maternal Age? One explanation for why meiotic segregation errors are more prevalent in older women is that cohesion between sister chromatids deteriorates with age and renders recombinant chromosomes susceptible to missegregation. Why do chromosomal abnormalities increase with age? A woman age 35 years or older is at higher risk of