How Does Oxygen Bind To Hemoglobin?

How Does Oxygen Bind To Hemoglobin? Oxygen binds reversibly to haem, so each haemoglobin molecule can carry up to four oxygen molecules. Haemoglobin is an allosteric protein; the binding of oxygen to one haem group increases the oxygen affinity within the remaining haem groups. When does oxygen bind to hemoglobin? Oxygen binds reversibly to haem,