Which Cell Organelle Is First Damage In Hypoxia?

Which Cell Organelle Is First Damage In Hypoxia? Mitochondria act as signaling organelles in low-oxygen conditions. Hypoxia (0.5–3% oxygen) increases mitochondrial ROS that activate transcription of adaptive genes. Anoxia (0–0.5% oxygen) initiates mitochondrial outer membrane permeabilization (MOMP) to activate cell death. What function of the cell is interrupted during hypoxia? During hypoxic injury blood flow