Can Homologous Recombination Repair Double-Strand Breaks?
Can Homologous Recombination Repair Double-Strand Breaks? DNA double-strand breaks are repaired by means of two main mechanisms: nonhomologous end joining and homologous recombination (see Figure 1). Both mechanisms operate in all eukaryotic cells that have been examined but the relative contribution of each mechanism varies. Can homologous recombination repair broken replication forks? Homologous recombination is