What Causes Congenital Adrenal Hyperplasia?
What Causes Congenital Adrenal Hyperplasia? Congenital adrenal hyperplasia is an inherited condition caused by mutations in genes that code for enzymes involved in making steroid hormones in the adrenal glands. The most common enzyme defect, 21-hydroxylase deficiency, leads to excess amounts of male hormones being produced by the adrenal glands. How do babies get CAH?