What Do Mesangial Cells Do?

What Do Mesangial Cells Do? Mesangial cells provide structural support to the glomerular tuft, produce and maintain mesangial matrix, communicate with other glomerular cells by secreting soluble factors, and may contribute to the glomerular capillary flow via their contractile properties. What is mesangial proliferative nephritis? Specialty. Nephrology. Mesangial proliferative glomerulonephritis is a form of glomerulonephritis