How Is Lantus Metabolized?

How Is Lantus Metabolized? Insulin glargine is metabolized in the liver into two active metabolites with similar activity to insulin: 21a-Gly-human insulin (M1) and 21a-Gly-des-30b- threonine insulin (M2), with M1 being the predominant metabolite. How is Lantus metabolised? Mechanism of Action: The primary activity of insulin, including insulin glargine, is regulation of glucose metabolism. Insulin