What Are The Components Of The Mitotic Spindle? The mitotic spindle is a special device essential for chromosome segregation ( mitosis) during cell division. It consists of three parts, chromosomes, two asters and a spindle region (Fig. 1). The overall shape of the mitotic spindle is due to microtubules, which are made of α and
At Which End Do Kinetochore Microtubules Shorten? During poleward movement of the autosomes in anaphase, the bundled region shortens by about 0.25 microm for each 1 microm the chromosome moves poleward; this suggests that, during anaphase, 75% of the kinetochore microtubule shortening occurs at the pole end. What end of microtubules do Kinetochores bind to?
Is Tubulin A GTPase? Tubulin has GTPase activity and the GTP molecules associated with β-tubulin molecules are hydrolyzed shortly after being incorporated into the polymerizing microtubules. GTP hydrolysis alters the conformation of the tubulin molecules and drives the dynamic behavior of microtubules. What type of substance is tubulin? The tubulin proteins α- and β polymerize