What Drug Makes You Grind Your Jaw?

What Drug Makes You Grind Your Jaw? What drug makes you grind your jaw? Bruxism is an under-recognised adverse drug reaction particularly associated with use of antipsychotics and selective serotonin reuptake inhibitors. A recent systematic review of case reports found it was most commonly reported with fluoxetine, venlafaxine and sertraline. Can drugs cause jaw clenching?