Can Prescription Pain Meds Affect Menstrual Cycle?

Can Prescription Pain Meds Affect Menstrual Cycle? If you have more bleeding than normal, talk to your doctor. Other painkillers known as nonsteroidal anti-inflammatory drugs (NSAIDs), which include ibuprofen and naproxen, have been shown to have the opposite effect. They can make the flow lighter during your period. Can hydrocodone cause irregular periods? Hydrocodone is