What Laboratory Finding Distinguishes Leukemoid Reaction From CML?

What Laboratory Finding Distinguishes Leukemoid Reaction From CML? Historically, various clues including the leukocyte alkaline phosphatase score and the presence of basophilia were used to distinguish CML from a leukemoid reaction. How can you distinguish between a CML and an leukemoid reaction? CML must be differentiated from leukemoid reactions, which usually produce WBC counts lower