How Do You Break Down Metabolites?
How Do You Break Down Metabolites? Once in the liver, enzymes convert prodrugs to active metabolites or convert active drugs to inactive forms. The liver’s primary mechanism for metabolizing drugs is via a specific group of cytochrome P-450 enzymes. How drugs are metabolized? Drugs can be metabolized by oxidation, reduction, hydrolysis, hydration, conjugation, condensation, or