How Does E. Coli Break Down Glucose?

How Does E. Coli Break Down Glucose? In E. coli, glucose metabolism mainly relies on the EMPP and the OPPP, while the EDP primarily remains inactive except during growth with gluconate [2]. The EDP utilizes only five enzymes to produce one pyruvate, one glyceraldehyde-3-phosphate, and one NADPH per glucose molecule (Fig. 1). Why does E.