Do Prokaryotes Have Mismatch Repair?

Do Prokaryotes Have Mismatch Repair? Prokaryotic cells possess mismatch repair systems that are characterized by short excision repair tracts (typically 20 nucleotides or less) (28). They have a relatively restricted specificity with respect to the mismatches that they repair and are operational only within a limited sequence context (29). Do bacteria have mismatch repair? Abstract.