Why Is RA Worse In The Morning?

Why Is RA Worse In The Morning? These symptoms closely follow the circadian rhythm of the pro-inflammatory cytokine, interleukin (IL)-6. In RA, the increase in nocturnal anti-inflammatory cortisol secretion is insufficient to suppress ongoing inflammation, resulting in the morning symptoms characteristic of RA. Why is my rheumatoid arthritis worse in the morning? Why You’re Achy