How Is Smooth Muscle Contraction Different From Skeletal Muscle Contraction?

How Is Smooth Muscle Contraction Different From Skeletal Muscle Contraction? Stimulation of both muscle cells lead to an increase in cytosolic calcium. … In skeletal muscle, calcium causes tropomyosin to shift, exposing the myosin-binding site on actin and starting contraction. In smooth muscle, calcium activates a kinase that phosphorylates light chains on myosin, leading to