mutant strains

Why Is An Ames Test Sometimes Called A Reverse Mutation Assay?

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Why Is An Ames Test Sometimes Called A Reverse Mutation Assay? This is to say that when a mutagenic event occurs, base substitutions or frameshifts within the gene can cause a reversion to amino acid prototrophy. This is the reverse mutation. Why is the Ames test considered a reversion test? Induction of new mutations replacing

What Is The Bacterial Strain That Was Used By Ames To Develop The Test?

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What Is The Bacterial Strain That Was Used By Ames To Develop The Test? Ames test devised by a scientist “Bruce Ames” is used to assess the potential carcinogenic effect of chemicals by using the bacterial strain Salmonella typhimurium. This strain is mutant for the biosynthesis of histidine amino acid. As a result they are