What Causes Synaptic Vesicles To Release From Their Protein Anchors?

What Causes Synaptic Vesicles To Release From Their Protein Anchors? When an action potential depolarizes the presynaptic plasma membrane, Ca2 +-channels open, and Ca2 + flows into the nerve terminal to trigger the exocytosis of synaptic vesicles, thereby releasing their neurotransmitters into the synaptic cleft (Fig. … The synaptic vesicle cycle. What triggers synaptic transmission?

What Are The Steps Of Neurotransmitter Release?

What Are The Steps Of Neurotransmitter Release? Neurotransmitter release from the presynaptic terminal consists of a series of intricate steps: 1) depolarization of the terminal membrane, 2) activation of voltage-gated Ca2 + channels, 3) Ca2 + entry, 4) a change in the conformation of docking proteins, 5) fusion of the vesicle to the plasma membrane,