Which Chemical Group Is At The 5 End Of A Single Polynucleotide Strand? Adjacent nucleotides in a polynucleotide are linked by phosphodiester bonds. The entire strand has a chemical directionality: the 5′ end with a free hydroxyl or phosphate group on the 5′ carbon of the sugar, and the 3′ end with a free hydroxyl
Why Does DNA Need To Be Unwound And Separated? Before replication can occur, the length of the DNA double helix about to be copied must be unwound. … Once the DNA strands have been unwound, they must be held apart to expose the bases so that new nucleotide partners can hydrogen-bond to them. What happens
What Is The Only Part Of A Nucleotide That Changes? Base substitution For example, during replication, a thymine nucleotide might be inserted in place of a guanine nucleotide. With base substitution mutations, only a single nucleotide within a gene sequence is changed, so only one codon is affected (Figure 1). What is the part of