Can You Take Grapefruit With Percocet?

Can You Take Grapefruit With Percocet? GENERALLY AVOID: Grapefruit juice may increase the plasma concentrations of oxycodone. Should you avoid grapefruit with oxycodone? Mixing the prescription painkiller oxycodone with grapefruit can cause serious breathing problems, and adding the fruit to a dose of the popular statin simvastatin, or Zocor, can lead to rhabdomyolysis, a breakdown