ornithine work

Does The Urea Cycle Regenerate Orinithine? Citrulline exits the mitochondria and condenses with aspartate to produce argininosuccinate. This compound is then cleaved to arginine and fumarate by argininosuccinate lyase. Arginine is hydrolyzed by arginase, thus releasing urea and regenerating ornithine. Is ornithine formed in urea cycle? Arginine is cleaved by arginase to form urea and