Can Calcium Release Stimulate Camp?
Can Calcium Release Stimulate Camp? IP3-evoked calcium release from SR stimulates calcium-activated adenylyl cyclases (AC8 and AC1) leading to production of cAMP and PKA, which in turn phosphorylates target proteins, L-type calcium channels (LTCC), ryanodine receptors (RyR) and phospholamban (PLB) associated with sarcoplasmic-endoplasmic reticulum … Does calcium inhibit cAMP? An increased intracellular Ca2+ concentration caused