How Does The Praziquantel Is Affecting In The Schistosoma Worms?

How Does The Praziquantel Is Affecting In The Schistosoma Worms? mansoni worms induced by praziquantel has been explained by the change in the permeability of the parasite to Ca2 +, which results in an increased calcium influx into the worm and an induction of sustained contraction of worm musculatures. How does praziquantel work for schistosomiasis?