Is HRT Made From Pregnant Horse Urine?

Is HRT Made From Pregnant Horse Urine? The estrogen-replacement drug Premarin, prescribed to menopausal women, is made from horse urine; in fact, the drug’s name is short for PREgnant MARes’ urINe. About 750,000 mares are impregnated each year for the sole purpose of collecting their estrogen-rich urine. What medication is made from mare urine? Premarin,