Can I Cancel A Prepaid Hotel Room Thru Amex Travel?

Can I Cancel A Prepaid Hotel Room Thru Amex Travel? To modify a reservation you must cancel and rebook your reservation. You can cancel and rebook your reservation on AmexTravel.com or by calling a representative of AmexTravel.com at 1-800-297-2977. Can you cancel a hotel you booked? You do not have an automatic right of cancellation.