How Many Fights Did Floyd Mayweather Lose?

How Many Fights Did Floyd Mayweather Lose? Floyd Mayweather Jr. Total fights 50 Wins 50 Wins by KO27 Losses0 Did Floyd Mayweather ever lost a fight? In the semi-final, Floyd Mayweather lost via a decision. The controversial result was accentuated by the match referee when he accidentally raised the American’s hand, thinking he had won.