How Do Proto-Oncogenes Affect The Cell Cycle?

How Do Proto-Oncogenes Affect The Cell Cycle? Oncogenes in their proto-oncogene state drive the cell cycle forward, allowing cells to proceed from one cell cycle stage to the next. This highly regulated process becomes dysregulated due to activating genetic alterations that lead to cellular transformation. Do proto-oncogenes stimulate the cell cycle? Mutations in proto-oncogenes are