Is MTOR A Protein? The mTOR protein belongs to the PI3K pathway activated by insulin, nutrients and growth factors. The PI3K pathway involves the Akt kinase, an upstream regulator of mTOR. … A wide body of evidence supports the role of mTOR in cell signaling related to cell growth and proliferation. What is mTOR made
What Is MTOR Activation? Mechanistic target of rapamycin (mTOR) is a sensor of metabolic stress and integrator of environmental cues. Activation of mTOR complex 1 (mTORC1) is triggered by oxidative stress, amino-acid levels and endosomal traffic to the lysosome by small GTPases such as Rab4A. What stimulates mTOR? Multiple factors and pathways affect mTORC1 activity