What Happens If The Kidney Produces Too Much Renin?

What Happens If The Kidney Produces Too Much Renin? 12) Reninoma. Reninomas are rare tumors of the kidney cells that make renin (juxtaglomerular cell tumors). They produce excessive amounts of renin, resulting in severe hypertension, high aldosterone levels, and low blood potassium levels [22, 23]. What does it mean when your renin level is high?