How Does Streptomycin Inhibit Protein Synthesis?

How Does Streptomycin Inhibit Protein Synthesis? Streptomycin is an aminoglycoside. It works by blocking the ability of 30S ribosomal subunits to make proteins, which results in bacterial death. What effect does streptomycin have on protein synthesis? STREPTOMYCIN affects bacterial protein synthesis in vitro by interfering with ribosomal functions1, 2. For example, it inhibits polypeptide synthesis