signaling pathway

What Is MTOR Activation?

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What Is MTOR Activation? Mechanistic target of rapamycin (mTOR) is a sensor of metabolic stress and integrator of environmental cues. Activation of mTOR complex 1 (mTORC1) is triggered by oxidative stress, amino-acid levels and endosomal traffic to the lysosome by small GTPases such as Rab4A. What stimulates mTOR? Multiple factors and pathways affect mTORC1 activity

What Is The Difference Between Canonical And Noncanonical?

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What Is The Difference Between Canonical And Noncanonical? As their names suggest, these pathways belong to one of two categories: canonical or noncanonical. The difference between the categories is that a canonical pathway involves the protein β-catenin while a noncanonical pathway operates independently of it. What is the difference between canonical and non-canonical pathways? As