What Is A Sub Group? A subgroup of a group G is a subset of G that forms a group with the same law of composition. For example, the even numbers form a subgroup of the group of integers with group law of addition. Any group G has at least two subgroups: the trivial subgroup
What Is The Problem With Subgroup Analysis? The limitations of subgroup analyses are well established—false positives due to multiple comparisons, false negatives due to inadequate power, and limited ability to inform individual treatment decisions because patients have multiple characteristics that vary simultaneously. What is subgroup analysis in clinical trials? By “subgroup analysis,” we mean any