tertiary carbons

Can Tertiary Carbons Undergo SN2?

by

Can Tertiary Carbons Undergo SN2? Here’s another tenet of organic chemistry that can be crossed out of the textbooks: Tertiary carbons can’t undergo bimolecular nucleophilic substitutions, also known as SN2 reactions. Why can SN2 happen on a tertiary carbon? Quick N’ Dirty Rule #2: If the substrate is tertiary, we can rule out SN2, because

Can Sn2 Happen On A Tertiary Carbon?

by

Can Sn2 Happen On A Tertiary Carbon? Can sn2 happen on a tertiary carbon? nucleophilic substitutions Why do tertiary carbons not undergo SN2? The reaction of hydroxide ion with chloromethane occurs in a single step. Alkyl substituents decrease the rates of SN2 reactions by interfering with the approach of the nucleophile. In 1-bromo-2,2-dimethylpropane, steric hindrance