Which Patients May Be Administered Tissue Plasminogen Activator Safely? Tissue plasminogen activator (tPA) is an intravenous medicine given for ischemic stroke – a stroke caused by a blood clot – that can dissolve the stroke-causing clot. Studies show that people who receive tPA within 3 hours – up to 4.5 hours in some patients –
Who Cannot Receive Thrombolytic? Thrombolytic therapy cannot be recommended for persons excluded from the NINDS Study6 for one of the following reasons: (1) current use of oral anticoagulants or a prothrombin time greater than 15 seconds (International Normalized Ratio [INR] greater than 1.7); (2) use of heparin in the previous 48 hours and a …
What Are The Contraindications For Thrombolytic Therapy? Recent intracranial hemorrhage (ICH) Structural cerebral vascular lesion. Intracranial neoplasm. Ischemic stroke within three months. Possible aortic dissection. Active bleeding or bleeding diathesis (excluding menses) When should thrombolytic therapy not be used? Generally, thrombolytics may not be given if you have: A recent head injury. Bleeding problems. Bleeding