What Pain Reliever Can I Take With Trazodone?

What Pain Reliever Can I Take With Trazodone? Yes you can take trazodone with tylenol pm or melatonin. What medications should not be taken with Trazodone? Examples of these drugs include: Monoamine oxidase inhibitors (MAOIs), such as isocarboxazid, phenelzine, tranylcypromine, or selegiline. You shouldn’t take trazodone with MAOIs or within 14 days of taking them.