What Happens If You Eat Grapefruit While Taking Hydrochlorothiazide?
What Happens If You Eat Grapefruit While Taking Hydrochlorothiazide? Grapefruit contains compounds known as furanocoumarins that block the CYP3A4 enzymes. When grapefruit juice is consumed, the enzyme’s ability to break down the drug for elimination is decreased. Blood levels of the drug may rise, resulting in a risk for new or worsened side effects. Can